luchtschip schreef op 18 oktober 2020 20:34:
Dr Eric Feigl Ding ;
HOLY COW—"In a *young, low-risk* population with ongoing #COVID19 symptoms, almost 70% of individuals have impairment in 1 or more organs 4 months after initial symptoms of #SARSCoV2 infection"
This is serious. It’s a young population too.
pbs.twimg.com/media/EklI0NOXIAEAC-T?f...1 Multi-organ impairment in low-risk individuals with long COVID
2 Andrea Dennis PhD1, Head of Biomarker Science, Perspectum en meerdere specialisten
Findings: Between April and September 2020, 201 individuals (mean age 44 (SD 11.0)
55 years, 70% female, 87% white, 31% healthcare workers) completed assessments following
56 SARS-CoV-2 infection (median 140, IQR 105-160 days after initial symptoms). The
57 prevalence of pre-existing conditions (obesity: 20%, hypertension: 6%; diabetes: 2%; heart
58 disease: 4%) was low, and only 18% of individuals had been hospitalised with COVID-19.
59 Fatigue (98%), muscle aches (88%), breathlessness (87%), and headaches (83%) were the
60 most frequently reported symptoms. Ongoing cardiorespiratory (92%) and gastrointestinal
61 (73%) symptoms were common, and 42% of individuals had ten or more symptoms.
62 There was evidence of mild organ impairment in heart (32%), lungs (33%), kidneys (12%),
63 liver (10%), pancreas (17%), and spleen (6%). Single (66%) and multi-organ (25%)
64 impairment was observed, and was significantly associated with risk of prior COVID-19
65 hospitalisation (p<0.05).
66 Interpretation:
In a young, low-risk population with ongoing symptoms, almost 70% of
67 individuals have impairment in one or more organs four months after initial symptoms of
68 SARS-CoV-2 infection. There are implications not only for burden of long COVID but also
69 public health approaches which have assumed low risk in young people with no
70 comorbidities.
www.medrxiv.org/content/10.1101/2020....