Vervolg:
About the consortium partners:
Ospedale Pediatrico Bambino Gesu´ OPBG (Rome, Italy) is the largest paediatric Hospital and research center in Europe, providing over 1.550.000 healthcare services each year to children and adolescents from all over the world. OPBG pursues excellency in health care through advanced research and clinical activities, while improving processes to exploit the progress of biomedical science. The Hospital’s clinical activities run side by side with its sci- entific research, aiming at constantly improving and innovating diagnostic and therapeutic procedures. OPBG’s Research Laboratories are located in a 5,000 sqm research facility, fully equipped with high-tech systems, supporting genomics, metagenomics, metabolomics, pro- teomics, microarray technology, cytogenetic and FISH applications, cytofluorimetry and cell sorting, cell and molecular biology. Within the Research Laboratories the team led by the Immunologist Dr Alessandra Fierabracci has established potency assays for evaluating the immunomodulatory activity of MSC-derived exosomes in vitro.
The IRCCS-Istituto di Ricerche Farmacologiche “Mario Negri” (www.marionegri.it) in Milan, Italy is a non-profit biomedical research institute. The Institute’s constant research areas include cardiovascular, psychiatric and neurological diseases, and tumours. Over the years, in line with technical advances, research has spread into the fields of environment and health, kidney diseases, organ transplantation, and rare diseases,
The Institute works regularly with various associations, hospital groups with different specialties, general practitioners, and nurses, setting up nation-wide cooperation networks. Underlying all this is basic research in pharmacokinetics, pharmacology, immunology, cell biology, genomics, proteomics, and metabolomics; it organizes controlled randomized clinical trials, studies on cohorts of elderly people, systemic reviews and meta-analyses.
Dr Annamaria Vezzani is Head of the Laboratory Experimental Neurology, Dept of Neuroscience, and she will be contributing to the project by sharing her long standing expertise with animal models of epilepsy and neuroinflammation to test the therapeutic anticonvulsive potential of extracellular vesicles and provide proof-of-concept evidence for clinical applications.
The department of Woman’s and Child’s Heath of the University of Padua is a 269-bed tertiary paediatric academic care centre, serving the entire North East region of Italy, devoted to provide excellence in patient’s care, teaching and research, also including a ten-store research building. It is one of the eleven fully recognised Italian Children’s Hospitals.
The University of Padova was founded in 1222. It includes 32 Departments, 1 University Hospital, 1 Veterinary Hospital, 1 Experimental Farm, 1 School of Excellence. It counts 61,000 Students and 12,000 Graduates per year.