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Third of S.Korea COVID-19 patients improve with remdesivir

Jul. 13, 2020 4:50 AM ET|About: Gilead Sciences, Inc. (GILD)|By: Yoel Minkoff, SA News Editor
The Korea Centers for Disease Control and Prevention is reporting results from a first group of 27 patients given Gilead Sciences' (NASDAQ:GILD) remdesivir in different hospitals.

One in three South Korean patients seriously ill with COVID-19 showed an improvement in their condition, though more research is needed to determine if the improvement was attributable to the drug or other factors like immunity and other therapies.

Several other countries have added the drug to the list of treatment for the disease caused by the coronavirus.

On Friday, Gilead said an analysis showed remdesivir helped reduce the risk of death in severely ill COVID-19 patients but cautioned that rigorous clinical trials were needed to confirm the benefit.
Nou Endless als die 62% verbetering blijft staan dan moet dit iets met de koers doen. Gisteren was er ook een behoorlijke stijging maar misschien wel op dit nieuws, ik weet het niet.
Innovation Pharma's Brilacidin shows encouraging anti-SARS-CoV-2 action in preclinical testing

Jul. 20, 2020 7:52 AM ET|About: Innovation Pharmaceuti... (IPIX)|By: Douglas W. House, SA News Editor
Innovation Pharmaceuticals (OTCQB:IPIX) announces new data from ongoing lab testing of Brilacidin for COVID-19.

In a human lung epithelial cell line, recently released data showed that Brilacidin reduced the coronavirus viral load by 95% and 97%, respectively, at two concentrations tested.

The new results, based on the same assay method, demonstrated that a concentration 50% below the lower of the two previously tested concentrations of Brilacidin inhibited the coronavirus by ~90%.

The company cites a Nature-published article that showed Gilead Sciences' (NASDAQ:GILD) remdesivir achieved 50% inhibition of SARS-CoV-2 in a time-of-addition experiment in animal cells.

The data will be submitted for publication.

A Phase 2 clinical trial should launch in Q4.

Ooievaar schreef op 14 juli 2020 09:21:

Nou Endless als die 62% verbetering blijft staan dan moet dit iets met de koers doen. Gisteren was er ook een behoorlijke stijging maar misschien wel op dit nieuws, ik weet het niet.

Ze zijn goed bezig (zie tweet) niet alles draait om remdesivir
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Health Canada has authorized the use of Gilead Sciences Canada Inc.’s remdesivir drug to treat people with severe COVID-19 symptoms on Tuesday, making this the first drug the regulator has approved to treat the virus.
The use of remdesivir is authorized only under certain conditions, Health Canada said. It has been approved for use in adults and adolescents aged 12 years or older.
Health Canada’s other conditions include that the manufacturer ensures the continued safety, efficacy, and quality of the drug. The regulator said it will closely monitor how remdesivir is prescribed to patients and will take action if any concerns arise.
"We appreciate Health Canada's expedited review of Veklury (the brand name for remdesivir) in recognition of the urgent need to treat COVID-19 patients in Canada," Gilead Sciences Canada General Manager Melissa Koomey said in a release Tuesday. "We are thankful for their collaboration and leadership, as we together work to respond to this public health emergency."
The drug has been given emergency or conditional authorization in some other countries including the United States, Japan, Europe and Australia.
In Canada, some COVID-19 patients have already been treated with remdesivir under the regulator's ?Special Access Program.
Gilead Sciences files U.S. application for remdesivir for COVID-19

Aug. 10, 2020 12:13 PM ET|About: Gilead Sciences, Inc. (GILD)|By: Douglas W. House, SA News Editor
Gilead Sciences (GILD -1.7%) has completed its rolling marketing application to the FDA seeking full approval of Veklury (remdesivir) for the treatment of severely ill hospitalized COVID-19 patients. It initiated the process on April 8.

The FDA approved the emergency use of the antiviral for these patients on May 1. It remains the only medicine to receive the nod in the U.S. to date. It is also available in Europe, Japan, India, Australia and Canada.
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